Huss A, Spoerri A, Egger M, Röösli M; for the Swiss National Cohort Study.
The relation between residential magnetic field exposure from power lines
and mortality from neurodegenerative conditions was analyzed among 4.7
million persons of the Swiss National Cohort (linking mortality and census
data), covering the period 2000-2005. Cox proportional hazard models were
used to analyze the relation of living in the proximity of 220-380 kV power
lines and the risk of death from neurodegenerative diseases, with adjustment
for a range of potential confounders.
Overall, the adjusted hazard ratio for
Alzheimer’s disease in persons living within 50 m of a 220-380 kV power line
was 1.24 (95% confidence interval (CI): 0.80, 1.92) compared with persons
who lived at a distance of 600 m or more. There was a dose-response relation
with respect to years of residence in the immediate vicinity of power lines
and Alzheimer’s disease: Persons living at least 5 years within 50 m had an
adjusted hazard ratio of 1.51 (95% CI: 0.91, 2.51), increasing to 1.78 (95%
CI: 1.07, 2.96) with at least 10 years and to 2.00 (95% CI: 1.21, 3.33) with
at least 15 years. The pattern was similar for senile dementia. There was
little evidence for an increased risk of amyotrophic lateral sclerosis,
Parkinson’s disease, or multiple sclerosis.