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Cell Phone Use and Risk of Brain Cancer

 

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February 12, 2012

In my last post I examined the epidemiology of brain tumors using a summary of the latest data from the United States. The summary noted the slight decline in the number of malignant brain cancers over the last twenty years.

One area of concern that is receiving increased attention is the potential for cell phone risk to raise the risk of brain cancers.

Obviously if cell phone use was a very large effect one might have expected an increase in the rates of brain tumors and cancer over the last twenty years. This corresponding to the time when cell phone use has increased dramatically in the U.S. and around the world.

Multiple case control studies have been completed examining this possible association and the majority of studies have not demonstrated a significant effect. One recent study from Frei in Denmark along with colleagues in France and Switzerland adds to the apparent safety of cell phones.

The key design elements of the Frei study included:
Study type: Cohort study using all individuals born in Denmark from April 1, 1968
Study groups: Cell phone subscribers status (subscribers versus non-subscribers) was identified via phone records and linked to centralized health records containing health registry information including presence or central nervous system tumors.
Confounding variables controlled: age, gender, education level, income
Outcome variable: incidence rates ratio with 95% confidence interal

This data set included over 300,000 individuals with a cell phone subscription and a larger group of control individuals.

The researchers grouped brain tumors into malignant gliomas, meningiomas (largely benign brain tumors) and a residual group of other brain tumor and cancer types.

The analysis showed the incidence rates for cell phones subscribers did not statistically differ from those who did not differ from those without cell phone subscriptions in any brain tumor or cancer group.

This is an important study. It represents a very large data set with comprehensive registry data that would be difficult to replicate in the United States health care system. The authors noted no specific increase in temporal lobe gliomas in the cell phone user group. This region of the brain would be the closest region to cell phone placement during calls and theoretically most likely to be affected if an association was present.

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