Cell Phone Use and Risk of
Brain Cancer

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February 12, 2012
In my last post I examined the epidemiology of brain tumors
using a summary of the latest data from the United States.
The summary noted the slight decline in the number of
malignant brain cancers over the last twenty years.
One area of concern that is receiving increased attention is
the potential for cell phone risk to raise the risk of brain
cancers.
Obviously if cell phone use was a very large effect one
might have expected an increase in the rates of brain tumors
and cancer over the last twenty years. This corresponding to
the time when cell phone use has increased dramatically in
the U.S. and around the world.
Multiple case control studies have been completed examining
this possible association and the majority of studies have
not demonstrated a significant effect. One recent study from
Frei in Denmark along with colleagues in France and
Switzerland adds to the apparent safety of cell phones.
The key design elements of the Frei study included:
Study type: Cohort study using all individuals born in
Denmark from April 1, 1968
Study groups: Cell phone subscribers status (subscribers
versus non-subscribers) was identified via phone records and
linked to centralized health records containing health
registry information including presence or central nervous
system tumors.
Confounding variables controlled: age, gender, education
level, income
Outcome variable: incidence rates ratio with 95% confidence
interal
This data set included over 300,000 individuals with a cell
phone subscription and a larger group of control
individuals.
The researchers grouped brain tumors into malignant gliomas,
meningiomas (largely benign brain tumors) and a residual
group of other brain tumor and cancer types.
The analysis showed the incidence rates for cell phones
subscribers did not statistically differ from those who did
not differ from those without cell phone subscriptions in
any brain tumor or cancer group.
This is an important study. It represents a very large data
set with comprehensive registry data that would be difficult
to replicate in the United States health care system. The
authors noted no specific increase in temporal lobe gliomas
in the cell phone user group. This region of the brain would
be the closest region to cell phone placement during calls
and theoretically most likely to be affected if an
association was present.
Spain, Madrid
Jackson, Mississippi
Tonga, Nuku'alofa
Yugoslavia, Belgrade
Richmond, Virginia
Seychelles, Victoria
Pembroke Pines, Florida
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Cote d'Ivoire, Yamoussoukro,
Logan City, Queensland
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